Research library / Rapamycin

TORC1 inhibition enhances immune function and reduces infections in the elderly

J Mannick, M Morris, H Hockey, G Roma, M Beibel, K Kulmatycki et al.. Science Translational Medicine. 2018.

Published 2026-10-15Sources checked 2026-10-151 sourceEverstack research teamHow we work

In plain language

Low-dose TORC1 inhibition was associated with fewer reported infections over a year.

Limits

A later phase 3 trial missed its primary endpoint.

Source

doi.org/10.1126/scitranslmed.aaq1564 · PubMed 29997249

Summary written by Everstack from the published abstract. Verified against Crossref on 2026-10-15. The authors do not endorse Everstack.