Research library / NAD+ (NR, NMN)

CPharmacokinetic study · Mice and 12 humans

Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

S Trammell, M Schmidt, B Weidemann, P Redpath, F Jaksch, R Dellinger et al.. Nature Communications. 2016.

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In plain language
NR is orally bioavailable; single doses of 100 to 1,000 mg raised blood NAD+ metabolites dose dependently.
Limits
Pharmacokinetics only; senior author tied to an NR maker.
Source
doi.org/10.1038/ncomms12948 · PubMed 27721479 · Free full text

Summary written by Everstack from the published abstract. Verified against Crossref on 2026-10-15. The authors do not endorse Everstack.