Research library / Reprogramming

DAnimal study · Mice

Loss of epigenetic information as a cause of mammalian aging

J Yang, M Hayano, P Griffin, J Amorim, M Bonkowski, J Apostolides et al.. Cell. 2023.

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In plain language
Inducing DNA breaks accelerated signs of aging in mice, partly reversed by OSK.
Limits
Debated interpretation.
Source
doi.org/10.1016/j.cell.2022.12.027 · PubMed 36638792 · Free full text

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